Theodore Maiman
http://en.wikipedia.org/wiki/Theodore_Harold_Maiman
Endre Mester
Endre Mester, a Hungarian physician, began a series of experiments (late 1960’s) with monochromatic light. In his early experiments, Mester was attempting to use “high powered” laser to destroy tumours and he implanted tumor cells beneath the skin of laboratory rats and zapped them with a customised ruby laser (red light). In fact the tumor cells were not destroyed by doses of the presumed high-power laser but Mester observed that, in many cases, the skin incisions made to implant the cancerous cells appeared to heal faster in treated animals compared to incisions of the control animals that were not treated with light.
This observation led Mester to design an experiment to ascertain his suspicion that treatment with red light accelerated healing of the surgical skin incisions he had made. The experiment was successful and showed that treatment with red light indeed produced faster healing of skin wounds. Fascinated by this development and wanting to learn more, Mester carried out other experiments showing that experimental skin defects, burns and human cases of ulcers arising from diabetes, venous insufficiency, infected wounds and bedsores also healed faster in response to his presumed laser treatment. It then turned out that Mester’s custom-designed ruby laser was weak and was not as powerful as he thought it to be. Instead of being photo-destructive, the low power light had no effect on the actual tumours. Indeed, it stimulated the skin to heal faster – just as sunlight may be beneficial in small amounts but destructive in high amounts. This amazing and accidental discovery opened the field of monochromatic light treatment.
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